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has subnanomolar potency in a TTK enzyme assay and inhibits the proliferation of cancer cell lines from diverse tumor tissue origin with IC50 from 11 to 290 nM at 5-day incubation time
InChiKey: DJBWDHVUJCXYBH-ONEGZZNKSA-N
TAS-102 (Trifluridine-tipiracil hydrochloride mixture) and CPT-11 is a promising treatment option for colorectal or gastric cancer
Prostogenat
Endoxifen Z-isomer hydrochloride Size:Contact [email protected] for quotation has subnanomolar potency in aEndoxifen Z isomer hydrochloride is the most important Tamoxifen metabolite responsible for eliciting the anti estrogenic effects of this drug in breast cancer cells expressing estrogen receptor alpha (ER). Endoxifen inhibits hERG tail currents at 50 mV in a concentration dependent manner with IC50 values of 1. 6 M. IC50 value: 1. 6 M Target: hERG Potassium Channel, Estrogen Receptor ERREndoxifen is considered a prodrug, since it has a much higher
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