TBK1/IKKε-IN-2 amide Tromethamine glycogen synthase kinase 3L and

glycogen synthase kinase 3L and cyclin-dependent kinase 2/cyclin A) underwent moderate inhibition

complete tumor regression of multiple myeloma (MM) xenografts and improves overall median survival in a systemic model of human MM

PHOtochemically TArgeting Chimera)

J Steroid Biochem Mol Biol

TBK1/IKKε-IN-2 amide Tromethamine glycogen synthase kinase 3L andTBK1 IKK IN 2 (Ikk epsilon in 1, IKK IN 1, MDK10496) is a dual inhibitor of TBK1 and IKK. Product information CAS Number: 1292310 49 6 Molecular Weight: 457. 52 Formula: C26H27N5O3 Synonym: Ikk epsilon in 1 IKK IN 1 MDK10496 Chemical Name: 5 (2 ((4 morpholinophenyl)amino)pyrimidin 4 yl) 2 ((tetrahydro 2H pyran 4 yl)oxy)benzonitrile Smiles: N#CC1=CC(=CC=C1OC1CCOCC1)C1=CC=NC(NC2C=CC(=CC=2)N2CCOCC2)=N1 InChiKey: BWABTWGSXHTHCG UHFFFAOYSA N InChi: