VX-745 Catalog No.:M7964-2 RS-1–induced lethality was accompanied by

RS-1–induced lethality was accompanied by the formation of microscopically visible RAD51 nuclear protein foci occurring in the absence of any DNA-damaging treatment

VX-745 Catalog No.:M7964-2 RS-1–induced lethality was accompanied byVX 745, is highly potent and selective p38 inhibitor (IC50 = 10 nM). VX 745 blocks TNF production in LPS stimulated HWB in vitro (IC50 = 177 nM). VX 745 displays excellent enzyme activity and selectivity, has a favorable pharmacokinetic profile, and demonstrates good in vivo activity in models of inflammation. Product information CAS Number: 209410 46 8 Molecular Weight: 436. 26 Formula: C19H9Cl2F2N3OS Synonym: VRT 031745 VD 31745 Neflamapimod