Istaroxime Catalog No.:M9594-10 Smiles: CN1C(=NC2=CC=CC=C12)C1C=C2C(N=C(CCC)N2CC2=CC=C(C=C2)C2=CC=CC=C2C(O)=O)=C(C)C=1

Smiles: CN1C(=NC2=CC=CC=C12)C1C=C2C(N=C(CCC)N2CC2=CC=C(C=C2)C2=CC=CC=C2C(O)=O)=C(C)C=1

LGK974 potently inhibits Wnt signaling in vitro and in vivo

InChiKey: TVQZAMVBTVNYLA-UHFFFAOYSA-N

Inhibition of NAALADase by 2-PMPA attenuates cocaine-induced relapse in rats: a NAAG-mGluR2/3-mediated mechanism

Istaroxime Catalog No.:M9594-10 Smiles: CN1C(=NC2=CC=CC=C12)C1C=C2C(N=C(CCC)N2CC2=CC=C(C=C2)C2=CC=CC=C2C(O)=O)=C(C)C=1Istaroxime, also known as PST 2744, is a positive inotropic agent that mediates its action through inhibition of sodium potassium adenosine triphosphatase (Na+ K+ ATPase). Na+ K+ ATPase inhibition increases intracellular sodium levels, which reverses the driving force of the sodium calcium exchanger, inhibiting calcium extrusion and possibly facilitating calcium entry. Additionally, Istaroxime increases intracellular calcium by improving the efficacy