Mesna Size:Solid 2 mg The Notch signaling pathway plays

The Notch signaling pathway plays an important role in cell-fate determination

and inhibited both anchorage-dependent and -independent proliferation in the pancreatic cancer cell line PANC-1

with an IC50 of ~50 nM with either substrate

CAS Number: 3604-87-3

Mesna Size:Solid 2 mg The Notch signaling pathway playsMesna is a sulfhydryl compound that is used to reduce the incidence of hemorrhagic cystitis associated with certain chemotherapeutic agents. Mesna is converted to a free thiol compound in the kidney, where it binds to and inactivates acrolein and other urotoxic metabolites of ifosfamide and cyclophosphamide, thereby reducing their toxic effects on the urinary tract during urinary excretion. Check for active clinical trials or closed clinical trials