Eltanexor Z-isomer Catalog No.:M20592-C Smiles: CN1C(=O)C2C(N=CN2C(=O)CNC2=CC=C(N=N2)C2C=CC=CC=2)N(C)C1=O

Smiles: CN1C(=O)C2C(N=CN2C(=O)CNC2=CC=C(N=N2)C2C=CC=CC=2)N(C)C1=O

AZD5438 showed significant antiproliferative activity in human tumor cell lines (IC(50) range

MAPK and PI 3-K and induces apoptosis in human glioblastoma cell lines (IC50 = 158 microM)

Thalidomide is initially promoted as a sedative

Eltanexor Z-isomer Catalog No.:M20592-C Smiles: CN1C(=O)C2C(N=CN2C(=O)CNC2=CC=C(N=N2)C2C=CC=CC=2)N(C)C1=OEltanexor Z isomer (KPT 8602 Z isomer) is the less active isomer of KPT 8602. KPT 8602 is a potent CRM1 inhibitor. IC50In Vitro: Eltanexor Z isomer exhibits different inhibitory effects on Z138, MM15, 3T3 cell lines, with IC50s of 100 nM 50 M, < 100 nM, > 30 M, respectively. In Vivo: Product information CAS Number: 1642300 78 4 Molecular Weight: 428. 29 Formula: C17H10F6N6O Chemical Name: (2Z) 3 {3 [3,5 bis(trifluoromethyl)phenyl] 1H 1,2,4 triazol 1