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PF-4989216 has PI3Kα Ki less than 1 nM and mTOR Ki more than 1 μM
Treatment of the PRP with Aspirin has no effect on the potency of Siguazodan
(-)-Arctigenin
Win 18446 (200 mg/kg
2-Methoxyidazoxan monohydrochloride Catalog No.:M21903-C PF-4989216 has PI3Kα Ki less2 Methoxyidazoxan monohydrochloride (RX821002 hydrochloride) is a highly selective alpha 2 adrenoceptor antagonist with little or no imidazoline antagonist effect. RX 821002 has markedly higher affinity for (guinea pig) alpha 2D adrenoceptors (pKd 9. 7) than for (rabbit) alpha 2A adrenoceptors (pKd 8. 2). Product information CAS Number: 109544 45 8 Molecular Weight: 270. 71 Formula: C12H15ClN2O3 Chemical Name: 2 [(2S) 2 methoxy 2,3 dihydro 1,4