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Phase 3 HoFH Lomitapide Study Investigators
Formula: C19H21BrN2O3S
GNF7156 was orally dosed to mice at 50 mg/kg twice a day for 14 days
135(5):1669-72
FH1 - Hepatocytes Functional Enhancer. CAS# 2719-05-3 090 Phase 3 HoFH Lomitapide StudyFH1, CAS No. 2719 05 3, is a potent and selective small molecule that enhances hepatocyte functions and promotes the differentiation and maturation of iPSC derived hepatocytes toward a more mature phenotype in vitro. FH1 was identified by a high throughput, cell based screening using primary human hepatocytes. It was added to the basal medium with or without OSM on day 21 after the initiation of differentiation of iPSCs and acted over a period of 9
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