A 412997 dihydrochloride Size:Contact [email protected] for quotation Chemical Name: sodium 2-((4-(3-methoxyphenyl)-5-(pyridin-2-yl)-4H-1

Chemical Name: sodium 2-((4-(3-methoxyphenyl)-5-(pyridin-2-yl)-4H-1

and cyclic adenosine monophosphate (cAMP) phosphodiesterase inhibitory effects

ClH/c1-24-18-6-3-13(9-19(18)25-2)7-8-20-11-14(21)12-26-15-4-5-16(22)17(23)10-15

Exploiting an Asp-Glu "switch" in glycogen synthase kinase 3 to design paralog-selective inhibitors for use in acute myeloid leukemia

A 412997 dihydrochloride Size:Contact [email protected] for quotation Chemical Name: sodium 2-((4-(3-methoxyphenyl)-5-(pyridin-2-yl)-4H-1A 412997 dihydrochloride is a selective agonist of dopamine D4 receptor with Ki values of 7. 9 and 12. 1 nM for human and rat D4 receptors, respectively . Dopamine D4 receptor is a G protein coupled receptor and is activated by dopamine. It plays an important role in cognition, Parkinsons disease, addictive behaviors and so on. A 412997 dihydrochloride is a selective dopamine D4 receptor agonist. In calcium flux functional assays, A 412997 activated