It has >100-fold selectivity over other methyltransferases tested
IDH2-C100 was used at 1-5 µM in vitro and cellular assays
105(41):15848-53
It inhibits class I HDAC with IC50 of 1
Forskolin - Adenylyl Cyclase Activator. CAS# 66428-89-5 60321 It has >100-fold selectivity overForskolin, CAS No. 66428 89 5, is a small molecule activator of adenylate cyclase (EC50~5 10 M) in a rapid and reversible manner, to increase the intracellular levels of cAMP. Forskolin is used in many stem cell differentiation conditions, such as potentiating neuronal differentiation. Product information CAS Number: 66428 89 5 Molecular Weight: 410. 50 Formula: C22H34O7 Chemical Name: (3R,4aR,5S,6S,6aS,10S,10aR,10bS) 6,10,10b trihydroxy 3,4a,7,7,10a