Pay in 4 interest-free payments of $8.00 Learn more
Ships within 48 hours · Estimated delivery Jul 30 - Aug 4
7 μM for inhibition of lipolysis in vitro
1007/s10549-010-1247-7
Molecular Weight: 462
Smiles: CC(C)C1=CN=C(C=C1NC1=CC=NC=C1C(=O)NC(CO)CO)C1=CC(Cl)=CC=C1F
DMH-1 - CAS# 1206711-16-1 60251 7 μM for inhibition ofDMH 1, CAS No. 1206711 16 1, is a second generation small molecule BMP inhibitor based on dorsomorphin. DMH 1 effectively inhibits the bone morphogenic protein (BMP) ALK2 receptor (IC50 = 108 nM). Treatment with DMH1 reduced lung metastasis and the tumors were less proliferative and more apoptotic. In the surrounding tumor microenvironment, treatment with DMH1 altered fibroblasts, lymphatic vessels and macrophages to be less tumor promoting. These
US$ 110.00
US$ 66.00
US$ 73.00
US$ 197.50
US$ 147.50
US$ 160.47
US$ 112.50
US$ 325.00
US$ 3488.50
US$ 155.00
US$ 167.00
US$ 276.00