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PROTAC ERα Degrader-1 acid NHS ester Ethoxysanguinarine inhibits viability and induces

SKU: 65984098322

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Description

Ethoxysanguinarine inhibits viability and induces apoptosis of colorectal cancer cells by inhibiting protein phosphatase 2A (CIP2A)

Nilsson-Ehle P

can increase prostaglandin PGE2 levels in bone marrow and other tissues

TGFβRI-IN-2 (compound 18) at 1 μM shows a 31% inhibition of MAP3K2 (MEKK2) with an IC50 value of 2

PROTAC ERα Degrader-1 acid NHS ester Ethoxysanguinarine inhibits viability and inducesPROTAC ER Degrader 1 comprises an ubiquitin E3 ligase binding group, a linker and a protein binding group. PROTAC ER Degrader 1 extracts from patent WO2017201449A1, compound P1. PROTAC ER Degrader 1 is an estrogen receptor alpha (ER) degrader. Product information CAS Number: 2417369 94 7 Molecular Weight: 1120. 29 Formula: C66H69N7O10 Chemical Name: (2S) N [(3S,4S) 7 cyano 5 (4 {[2 (2 {[(2 {4 [(1Z) 1 (4 hydroxyphenyl) 2 phenylbut 1 en 1

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