GSK2879552 dihydrochloride - LSD1 Inhibitor. CAS# 1902123-72-1 size:10mg solid Screening: Your brain on drugs

Screening: Your brain on drugs

1-diyl))bis(1

particularly for the p53R175 mutant

MDL-29951 is found to inhibit the human F16Bpase under these conditions (IC50=2

GSK2879552 dihydrochloride - LSD1 Inhibitor. CAS# 1902123-72-1 size:10mg solid Screening: Your brain on drugsGSK2879552 dihydrochloride, CAS No. 1902123 72 1, is a highly potent, selective and orally bioavailable irreversible inhibitor of Lysine Specific Demethylase 1 (LSD1). It is highly selective over related enzymes such as MAO A B. A proliferation screen of cell lines representing a number of tumor types indicated that small cell lung carcinoma (SCLC) is sensitive to GSK2879552s inhibition. It increases H3K4 methylation selectively at genomic regions