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26 μM) with several hydrophobic interactions
with an IC50 of <3 nM for DNA-PK and <0
H2O/c1-6(18-5-19(15
defined medium
CHK1-IN-4 Catalog No.:M30036-C 26 μM) with several hydrophobicCHK1 IN 4 (Compound 3) is a potent checkpoint kinase 1 (chk1) inhibitor, and potently inhibits chk1 phosphorylation in the tumor cells. CHK1 IN 4 has anti tumor activity. Product information CAS Number: 2120398 41 4 Molecular Weight: 444. 29 Formula: C18H18BrN7O2 Chemical Name: 5 ({5 [2 (3 aminopropoxy) 4 bromo 6 methoxyphenyl] 1H pyrazol 3 yl}amino)pyrazine 2 carbonitrile Smiles: COC1=CC(Br)=CC(OCCCN)=C1C1=CC(NC2=CN=C(C=N2)C#N)=NN1 InChiKey: