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IHC Host Rabbit Clone type rabbit monoclonal Target Background This gene encodes a member of a family of proteins containing one or more high mobility group DNA-binding motifs
Two control formats provided: Both E1A linear DNA Control (lyophilized) and E1A non-linear DNA Control are supplied so users can choose according to validation needs
This antibody is suitable for HCP coverage evaluations
LineGene 9600 plus
Human Noggin Coomassie Blue & Stains IHC Host Rabbit Clone typeBcakground Noggin is a secreted homodimeric glycoprotein that is an antagonist of bone morphogenetic proteins (BMPs) (1, 2). Human Noggin cDNA encodes a 232 amino acid (aa) precursor protein; cleavage of a 19 aa signal peptide generates the 213 aa mature protein which contains an N terminal acidic region, a central basic heparin binding segment and a C terminal cysteine knot structure (2). Secreted Noggin probably remains close to the cell surface due