MC1568 - Class IIa HDAC Inhibitor. CAS# 852475-26-4 0318 and could offer benefits including

and could offer benefits including a greater therapeutic index for treating T-cell malignancies

and vascular regrowth contribute to the antitumor properties of dual mTORC1/mTORC2 inhibitors

5 µM concentration in vitro and cellular assays

Chemical Name: (S)-2-((S)-2-(3

MC1568 - Class IIa HDAC Inhibitor. CAS# 852475-26-4 0318 and could offer benefits includingMC1568, CAS No. 852475 26 4, is a potent and selective inhibitor of class IIa histone deacetylases (HDACs), with IC50 of 100 nM for maize HD1 A. It is 34 fold more selective for HD1 A than HD1 B, 176 fold more selective for class I HDACs. It exhibits tissue selective inhibition between members of class II deacetylases in vivo; inhibits HDAC4 and HDAC5 in skeletal muscle and the heart without affecting HDAC3 activity. It arrests myogenesis through the