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PubMed Central PMCID: PMC3831715
In initial dose-ranging studies
TCO-PEG4-DBCO is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)
ARCC-4 hydrate
Nutlin-3 Catalog No.:M14226-2 PubMed Central PMCID: PMC3831715Nutlin 3 is a potent and selective Mdm2 (RING finger dependent ubiquitin protein ligase for itself and p53) antagonist with IC50 of 90 nM in a cell free assay; stabilizes p73 in p53 deficient cells. Product information CAS Number: 890090 75 2 Molecular Weight: 581. 49 Formula: C30H30Cl2N4O4 Chemical Name: 4 [4,5 bis(4 chlorophenyl) 2 [4 methoxy 2 (propan 2 yloxy)phenyl] 4,5 dihydro 1H imidazole 1 carbonyl]piperazin 2 one Smiles:
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